Desecration

A desecration is a religious act of defiling an object used in worship (usually to a pagan deity) so that nobody else will use it for that purpose.

Empath: The Luckiest Smurf stories
In the EMPATH: The Luckiest Smurf story series, the Antichrist figure in Tapper's Imaginarium fantasy setting depicting the time of the Tribulation desecrates the Jewish Temple that appears in that scenario by sacrificing a pig on the altar, preventing the Jews from ever using it for worshiping Jehovah God.