Smurphine

Smurphine is a painkiller used to treat serious injuries in Smurfs in the EMPATH: The Luckiest Smurf story series. It is administered through a hypodermic needle injected into a blood vessel so that it gives the Smurf fast pain relief. It has a relaxing euphoric effect that can be quite addictive, so the physician administering it to his or her patient must be careful in the dosage used.

Smurphine is rarely used outside of a medical care facility such as the Smurf Village Infirmary, and none other than licensed practictioners of medicine, such as Papa Smurf and Dabbler, are allowed to administer it. However, it has not stopped Smurfs from getting their hands on the substance to use it as a recreational drug. This has led to some near-fatal dosages that required Papa Smurf and Empath to intervene.

Smurphine is meant to be the Smurf analog to the real-life medical drug morphine.