Tobacco is a product made from dried leaves of the genus in the plant Nicotiana. It is the main ingredient in cigars and cigarettes and contains nicotine which is a very addictive drug for humans.
Empath: The Luckiest Smurf stories[]
Grandpa Smurf during his travels through the world in the EMPATH: The Luckiest Smurf story series has tried a sample of tobacco when he was staying with a Native American tribe in the North America continent. Grandpa considers tobacco to be so potent and addictive that he warns the other Smurfs not to even try smoking it.
Stinkweed is a plant that has a taste similar to tobacco.
Smurf Me Up! stories[]
In the Smurf Me Up! story "City of Dis", tobacco is used by the citizens of the city of Dis as they indulge in various types of pleasures, no matter how depraved.